Die Krebsgene BRCA1 und BRCA2 – as ovarian cancer susceptibility genes ..
Non-melanoma skin cancer: what drives tumor development and progression?
Krebs-Biologie – Prostatakrebs- Neue Heilungserkenntnisse durch programmierten Zelltod –
„Overexpression of Id-1 in prostate cancer cells promotes angiogenesis through the acivation of vascular endothelial growth factor (VEGF)
und mehr –
Carcinogenesis — Table of Contents Alert
A new issue of Carcinogenesis
has been made available:
October 2005; Vol. 26, No. 10
URL: http://carcin.oxfordjournals.org/content/vol26/issue10/index.dtl?etoc
COMMENTARY
BRCA1 and BRCA2 as ovarian cancer susceptibility genes
Heidi M. Sowter and Alan Ashworth
Carcinogenesis 2005 26: 1651-1656.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1651?etoc
Non-melanoma skin cancer: what drives tumor development and progression?
Petra Boukamp
Carcinogenesis 2005 26: 1657-1667.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1657?etoc
CANCER BIOLOGY
Overexpression of Id-1 in prostate cancer cells promotes angiogenesis
through the activation of vascular endothelial growth factor (VEGF)
Ming-Tat Ling, Tracy C.M. Lau, Chun Zhou, Chee Wai Chua, Wai Kei Kwok, Qi
Wang, Xianghong Wang, and Yong-Chuan Wong
Carcinogenesis 2005 26: 1668-1676.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1668?etoc
Spermidine/spermine N1-acetyltransferase transient overexpression restores
sensitivity of resistant human ovarian cancer cells to
N1,N12-bis(ethyl)spermine and to cisplatin
Gaetano Marverti, Maria Giuseppina Monti, Anthony E. Pegg, Diane E.
McCloskey, Saverio Bettuzzi, Alessio Ligabue, Andrea Caporali, Domenico
D’Arca, and Maria Stella Moruzzi
Carcinogenesis 2005 26: 1677-1686.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1677?etoc
The role of the cytoskeleton in differentially regulating
pressure-mediated effects on malignant colonocyte focal adhesion signaling
and cell adhesion
Vijayalakshmi Thamilselvan and Marc D. Basson
Carcinogenesis 2005 26: 1687-1697.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1687?etoc
Frequent activation of the hedgehog pathway in advanced gastric
adenocarcinomas
Xiaoli Ma, Kai Chen, Shuhong Huang, Xiaoli Zhang, Patrick A. Adegboyega,
B.Mark Evers, Hongwei Zhang, and Jingwu Xie
Carcinogenesis 2005 26: 1698-1705.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1698?etoc
The p160 family coactivators regulate breast cancer cell proliferation and
invasion through autocrine/paracrine activity of SDF-1{alpha}/CXCL12
Hiromitsu Kishimoto, Zhuo Wang, Poornima Bhat-Nakshatri, David Chang,
Robert Clarke, and Harikrishna Nakshatri
Carcinogenesis 2005 26: 1706-1715.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1706?etoc
Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in
human colorectal cancer cells
Jenq-Chang Lee, Chao-Hung Lee, Chun-Li Su, Chung-Wei Huang, Hsiao-Sheng
Liu, Chun-Nan Lin, and Shen-Jeu Won
Carcinogenesis 2005 26: 1716-1730.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1716?etoc
The Fanconi anemia group A protein modulates homologous repair of DNA
double-strand breaks in mammalian cells
Yun-Gui Yang, Zdenko Herceg, Koji Nakanishi, Ilja Demuth, Colette Piccoli,
Jocelyne Michelon, Gabriele Hildebrand, Maria Jasin, Martin Digweed, and
Zhao-Qi Wang
Carcinogenesis 2005 26: 1731-1740.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1731?etoc
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MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION
—————————————————————–
Roles of tumor suppressor and telomere maintenance genes in cancer and
aging–an epidemiological study
Jian Gu, Margaret R. Spitz, Hua Zhao, Jie Lin, H.Barton Grossman, Colin P.
Dinney, and Xifeng Wu
Carcinogenesis 2005 26: 1741-1747.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1741?etoc
The functional polymorphism in the matrix metalloproteinase-7 promoter
increases susceptibility to esophageal squamous cell carcinoma, gastric
cardiac adenocarcinoma and non-small cell lung carcinoma
Jianhui Zhang, Xia Jin, Shumei Fang, Rui Wang, Yan Li, Na Wang, Wei Guo,
Yimin Wang, Denggui Wen, Lizhen Wei, Zhiming Dong, and Gang Kuang
Carcinogenesis 2005 26: 1748-1753.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1748?etoc
Identification of BCRP as transporter of benzo[a]pyrene conjugates
metabolically formed in Caco-2 cells and its induction by Ah-receptor
agonists
Bettina Ebert, Albrecht Seidel, and Alfonso Lampen
Carcinogenesis 2005 26: 1754-1763.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1754?etoc
Polymorphisms of thymidylate synthase in the 5′- and 3′-untranslated
regions associated with risk of gastric cancer in South China: a
case-control analysis
Zhengdong Zhang, Yaochu Xu, Jianwei Zhou, Xinru Wang, Liwei Wang, Xu Hu,
Jiangtao Guo, Qingyi Wei, and Hongbing Shen
Carcinogenesis 2005 26: 1764-1769.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1764?etoc
TP53 mutation, allelism and survival in non-small cell lung cancer
Heather H. Nelson, Magnus Wilkojmen, Carmen J. Marsit, and Karl T. Kelsey
Carcinogenesis 2005 26: 1770-1773.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1770?etoc
Preferential induction of CYP1B1 by benzo[a]pyrene in human oral
epithelial cells: impact on DNA adduct formation and prevention by
polyphenols
Xia Wen and Thomas Walle
Carcinogenesis 2005 26: 1774-1781.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1774?etoc
Inhibition of adult liver progenitor (oval) cell growth and viability by
an agonist of the peroxisome proliferator activated receptor (PPAR) family
member {gamma}, but not {alpha} or {delta}
Belinda Knight, Bu B. Yeap, George C. Yeoh, and John K. Olynyk
Carcinogenesis 2005 26: 1782-1792.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1782?etoc
—————————————————————–
CARCINOGENESIS
—————————————————————–
The soy isoflavone genistein promotes apoptosis in mammary epithelial
cells by inducing the tumor suppressor PTEN
Bhuvanesh Dave, Renea R. Eason, S.Renee Till, Yan Geng, Michael C.
Velarde, Thomas M. Badger, and Rosalia C.M. Simmen
Carcinogenesis 2005 26: 1793-1803.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1793?etoc
Loss of p21WAF1/Cip1 in Gadd45-deficient keratinocytes restores DNA repair
capacity
Tomoko Maeda, Robin A. Espino, Eugene G. Chomey, Le Luong, Ather Bano,
Diana Meakins, and Victor A. Tron
Carcinogenesis 2005 26: 1804-1810.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1804?etoc
Novel genotoxicity assays identify norethindrone to activate p53 and
phosphorylate H2AX
Eike Gallmeier, Jordan M. Winter, Steven C. Cunningham, Saeed R. Kahn, and
Scott E. Kern
Carcinogenesis 2005 26: 1811-1820.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1811?etoc
DNA adduct and tumor formations in rats after intratracheal administration
of the urban air pollutant 3-nitrobenzanthrone
Eszter Nagy, Magnus Zeisig, Ken Kawamura, Yoshiharu Hisamatsu, Akiko
Sugeta, Shuichi Adachi, and Lennart Moller
Carcinogenesis 2005 26: 1821-1828.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1821?etoc
Human p53 knock-in (hupki) mice do not differ in liver tumor response from
their counterparts with murine p53
Maike Jaworski, Stephan Hailfinger, Albrecht Buchmann, Manfred Hergenhahn,
Monica Hollstein, Carina Ittrich, and Michael Schwarz
Carcinogenesis 2005 26: 1829-1834.
http://carcin.oxfordjournals.org/cgi/content/abstract/26/10/1829?etoc